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Wednesday 9th
 |
| 19:00 |
 Dinner |
| 21:00 |
 
Reception , Jazz Music in the Lobby |
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| Thursday 10th
|
| 07:00 |
 Breakfast |
| Session Drug Design and Dynamics
Chair: Mirek Cygler |
| 08:00 |
Opening Remarks Joel Sussman |
| 08:15 |
New spins on protein dynamics from NMR spectroscopy.
Frans A.A. Mulder, Ulrika Brath, Mikael Akke, Lewis E Kay
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| 08:45 |
Structure-based drug design on SARS protease and glutaminyl cyclase targets.
Andrew Wang
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| 09:15 |
From Genome to Drug Lead: Identification of a Small-Molecule Inhibitor of the SARS Virus.
Yuan-Ping Pang
|
| 09:45 |
Coffee Break & Posters |
| Session Function
Chair: Osnat Herzberg |
| 10:15 |
ANTICALINS: Protein Engineering of Lipocalins for Novel Binding Functions.
Arne Skerra
|
| 10:45 |
Use of the Yellow Fever Virus for the Expression of Heterologous Epitopes.
Richard Charles Garratt, Myrna C. Bonaldo, Marcos S. Freire, Mauricio Rodrigues, Ricardo Galler
|
| 11:15 |
Protein engineering using bacteriophage T4 foldon.
Vadim Mesyanzhinov
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| 11:45 |
Lunch |
| 13:15 |
 INPEC Business Meeting - Delegates Only |
| Session Folding and Unfolding
Chair: Adrian Goldman |
| 14:00 |
Transient Structures, Ensembles of Structures and Transition States in the
Protein Folding Process of a Four Helix Bundle – ACBP
Flemming Poulsen
|
| 14:30 |
Study of the gradual protein unfolding by NMR spectroscopy
Jianxing Song, Zheng Wei
|
| 15:00 |
A cytosolic complex for targeting proteins to mitochondria
Nick Hoogenraad
|
| 15:30 |
Role of disorder in protein interaction networks.
Peter Tompa
|
| 16:00 |
Coffee Break & Posters |
| Session Proteomics
Chair: Rick Wierenga |
| 16:30 |
Proteome comparison on D. Salexigens cells.
Belarmino A. Salvado Barata, Bruno M. C. Alexandre
|
| 17:00 |
Protein engineering to study the interaction between Ferredoxin NADP+ reductase and Feredoxin (or Flavodoxin).
Carlos Gomez-Moreno
|
| 17:30 |
Acetylcholinesterase: Key Enzyme in Neurotransmission Moonlights with Unexpected Additional Roles?.
Joel Sussman
|
| 18:00 |
Towards structural genomics of prophages.
Sankaran Krishnaswamy
|
| 19:00 |
Dinner |
| 20:15 |
 Night Tour of Botanical Gardens |
| 21:30 |
Israeli Folk Dancing in the Lobby |
|
| Friday 11th
|
| 07:00 |
Breakfast |
| 08:00 |
 Tour: Massada |
| 12:30 |
Lunch |
| Session Mechanisms
Chair: Kosuke Morikawa |
| 14:00 |
Inorganic pyrophosphate: one substrate, two mechanisms?.
Adrian Goldman
|
| 14:30 |
Crystal structure of the human urokinase plasminogen activator receptor bound to an antagonist peptide.
E. Stura, M.H. Le Du, M. Ploug, B. Gilquin, A. Menez
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| 15:00 |
Structure and mechanism of heparin and heparan sulfate degrading heparinase II from F. heparinum.
Miroslaw Cygler, David Shaya, Yunge Li, James Myette
|
| 15:30 |
Selectivity and promiscuity in protein:protein interactions controlling apoptosis.
Peter Colman, Doug Fairlie, Erinna Lee, Peter Czabotar, David Huang
|
| 16:00 |
Coffee Break & Posters |
| Session Architecture of Active Sites
Chair: Peter Colman |
| 16:30 |
The novel closed structure of an archaeal DNA ligase from Pyrococcus furiosus.
Kosuke Morikawa, H. Nishida, S. Kiyonari, Y. Ishino
|
| 17:00 |
Chasing the function of hypothetical proteins.
Osnat Herzberg
|
| 17:30 |
Loop-6 and loop-7 of triosephosphate isomerase: structural enzymological studies.
Rik Wierenga, Markus Alahuhta, Marco Casteleijn, Peter Neubauer
|
| 18:00 |
Determinants of IgA1 protease specificity.
Tony Warren, Emily Kwan, Jenny Woof, Jiazhou Qiu, Andrew Plaut
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| 19:00 |
Dinner |
| Session Engineering Proteins
Chair: Nick Hoogenraad |
| 20:00 |
Designed Ankyrin Repeats as Enzyme inhibitors.
Andreas Plueckthun, Patrick Amstutz, Kaspar Binz, Petra Parikez, Markus Gruetter
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| 20:30 |
Structural studies of the human chimerical plasminogen activator Amediplase® (K2tu-PA).
Doriano Lamba, Alberto Cassetta, Cecilia Bartolucci
|
| 21:00 |
Music and Dancing in the Lobby |
|
| Saturday 12th
|
| 07:00 |
Breakfast |
| 08:00 |
Tour Outings Options:
1. Hike in desert springs route
2. Dead Sea spa visit
|
| 12:30 |
Lunch |
| Session Protein Engineering Tools
Chair: Andreas Plueckthun |
| 14:00 |
Bioinformatics Tools for Structural Proteomics.
Jaime Prilusky
|
| 14:30 |
Simulating, Refining, and Modeling Supramolecular Complexes at Multi-resolution and Multi-length Scales
Jianpeng Ma
|
| 15:00 |
Progress and Bottlenecks in a Decade of CASP
John Moult
|
| 15:30 |
Coffee Break & Posters |
| Session Evolution
Chair: Tony Warren |
| 16:00 |
The spectacular ribosomal architecture: From protein making to folding via the
antibiotics binding pocket Ada Yonath
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| 16:30 |
Design of the active site architecture of an enzyme for evolution of new catalytic function.
Hak-Sung Kim, Hee-Sung Park, Sung-Hun Nam, Jin Kak Lee, Chang No Yoon
|
| 17:00 |
Evolution and Synthesis of New Function.
Jason Chin
|
| 17:30 |
Generation of structurally distinct ovine prion protein soluble oligomers.
Thomas Haertlé, Human Rezaei, Jeanne Grosclaude
|
| 18:00 |
Protein Evolution - the Theory and Practice.
Dan Tawfik
|
| 18:30 |
 Free Time |
| 20:00 |
Festive Dinner |
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| Sunday 13th
|
| 07:00 |
Breakfast |
| 08:30 |
 Transportation to the Weizmann Institute |
